Vermilion Parish amongst highest colon cancer rate in state

Vermilion Parish is one of nine more-at-risk parishes in Louisiana that has a high colorectal cancer incidence, based on a special study done by the LSU Health New Orleans School of Public Health’s Louisiana Tumor Registry.
This study appears to be the first to identify a high rate of cancer in a large, regional, US founder population, raising the possibility of a genetic predisposition.
The other at-risk parishes are Acadia, Assumption, Avoyelles, Evangeline, Jefferson Davis, LaFourche, Jeff Davis, St. Landry and St. Martin parish.
The research team chose to study the Acadian parishes where French is spoken as these parishes are home to the Cajun population that migrated to the region in the 1700’s from Canada and France.
The research team identified 18 Acadian parishes and stratified 2005-2009 cancer incidence data by age, ethnicity and gender by utilizing French language census data.
A total of 3,288 colorectal cancer cases were identified in the Acadian region and 11,737 in Louisiana.
They identified a subgroup of 9 parishes (including Vermilion) with higher proportions of French speakers, a marker for the Cajun population.
Colorectal cancer rates in whites and white males in the 18 parishes were statistically significantly higher than both Louisiana and US rates.
In the 9 parishes, rates increased further; whites had an incidence of 56.1 per 100,000, 13% higher than Louisiana and 23% higher than the US rate. In white males, incidence was 72.6 per 100,000, 19% higher than Louisiana and 37% higher than the US rate. If the 9-parish region were considered a “state,” white males would have the highest colorectal cancer incidence in the United States by 11% compared with other white male populations.
“This study has identified disproportionately high rates of colorectal cancer in the Acadian parishes of Louisiana,” says Dr. Karlitz. “The research highlights the importance of utilizing data made available by high-quality population-based cancer registries to identify at-risk populations that can have important implications with regard to health care delivery. Future studies to assess genetic and environmental risk factors will be necessary to better understand the colorectal cancer incidence in this population.”
“This study demonstrates the importance of the Louisiana Tumor Registry at the LSU Health New Orleans School of Public Health in identifying areas and populations at high risk of cancer. Without the population-based state registry, we would not have such data for cancer control and research,” notes Dr. Wu.
Concludes senior author Dr. Elizabeth Fontham, who is from the region, “This study has provided provocative findings of a potential link between high colorectal cancer risk and the Acadian population of south Louisiana. Additional studies in this population are important in order to better understand the roles of specific factors, both genetic and/or environmental.”

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